Yes. Whenever I've used acne washes and treatments with salicylic acid, my hand towels and pillowcases have become bleached. I would then use only old towels for my face. I just had a neighbor remark that her daughter's towels were losing color and bleaching. I told her it was due to salicylic acid products and she should switch to white towels and pillowcases. I have never had a problem with clothes, but I would think if one were using the products on the body, it would affect clothes in the same way.