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Old 11-27-2013, 03:47 AM
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Why do people with sepsis get hand and foot amputation?

I have seen reports of people with sepsis and also people with meningitis need to have hand and foot amputations becasue they get necrosis. But why would a infection lead to necrosis in the hands and feet? Also what are the amputation rates for sepsis and meningitis.
#2
Old 11-27-2013, 04:18 AM
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One of the symptoms of sepsis can be low blood pressure, low enough to be life-threatening. When that happens medication to raise it is given, which works by contracting small blood vessels which tends to reduce circulation to the extremities. In some cases, the dosages required to preserve life are so high that the blood vessels in the hands and feet are so contracted that insufficient blood reaches the hands and feet and those parts of the body die from lack of blood flow. This is what results in amputation.
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Old 11-27-2013, 05:03 AM
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I don't think so many cases are related to pharmaceuticals given as treatment.

Is the tci707 talking about Meningococcal - Its first signs are in the hands and feet and I think it loves to live there, and in the brain.
#4
Old 11-27-2013, 05:50 AM
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Sepsis can also cause disseminated intravascular coagulation, which basically means your blood starts to spontaneously clot. This can also cut off circulation to extremities, as well as internal organs and the brain.
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Old 11-27-2013, 09:52 AM
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As I understand it - One of the more common amputations is leg amputatons due to type II diabetes. As I understand it, when circulation starts to be affected, the sites that suffer most are the extremities. Poor blood flow leads to clots, chunks of flesh die and rot (gangrene) and of course, this spreads since nearby tissue need the blood flow that is cut off by the dead areas.
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Old 11-27-2013, 10:48 AM
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Quote:
Originally Posted by Broomstick View Post
Sepsis can also cause disseminated intravascular coagulation, which basically means your blood starts to spontaneously clot. This can also cut off circulation to extremities, as well as internal organs and the brain.
We have a winner!

DIC with its subsequent clots cutting off blood flow to peripheries like noses, fingers, hands, penises, feet, etc is the primary reason that septic patients need amputations.

Other parts of the body can be clotted off too, which is why some septic patients need hunks of bowel cut out.
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Old 11-27-2013, 10:51 AM
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I'd hate to have my penises amputated.
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#8
Old 11-27-2013, 10:52 AM
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Originally Posted by Patty O'Furniture View Post
I'd hate to have my penises amputated.
And your noses.
#9
Old 11-27-2013, 12:28 PM
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In my case, the whole mess started with a wound on my foot that I ignored/didn't notice (I'm a little fuzzy about my motivations at that time still) that turned septic and spread into the bone, then caused sepsis. By the time I was sick enough for someone to notice and insist I go to the ER, there was enough pedal real estate in necrosis that they couldn't really save anything below mid-calf. I was told that my blood chemistry on arrival was so bad that if I'd resisted going to the ER for another couple of hours I'd have been dead. All I know is that I was delirious for almost a week, only half-aware of what was actually going on.
#10
Old 11-27-2013, 12:41 PM
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Look at it this way: there aren't all that many non-extremity body parts that can be amputated without killing the patient. The bowel is mostly a closed system with some redundancy, so losing a length of intestine is not generally fatal. Contrast that with the heart; you can't just cut out a chunk of that tissue. Well, you can, but only a small piece.
#11
Old 11-27-2013, 03:53 PM
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Quote:
Originally Posted by Patty O'Furniture View Post
I'd hate to have my penises amputated.
Most people can get by with just one.
#12
Old 11-27-2013, 04:59 PM
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Quote:
Originally Posted by kunilou View Post
Most people can get by with just one.
Hell, most people get by with zero. One is the second-most-common configuration.
#13
Old 11-27-2013, 07:46 PM
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Originally Posted by leahcim View Post
Hell, most people get by with zero. One is the second-most-common configuration.
Actually, the average number of male penises is slightly less than one.
#14
Old 11-27-2013, 10:52 PM
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Originally Posted by Qadgop the Mercotan View Post
Actually, the average number of male penises is slightly less than one.
And, bringing it back around to this thread, the average number of legs per person is slightly less than two.
#15
Old 11-27-2013, 11:03 PM
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Quote:
Originally Posted by Qadgop the Mercotan View Post
Actually, the average number of male penises is slightly less than one.
Umm, what other kind of penises are there?
#16
Old 11-28-2013, 12:11 AM
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Female spotted hyenas have what is called a pseudo-penis. So, a female penis. Basically, it's an oversized clitoris, and the female mates and gives birth through it. She also has a pseudo scrotum.
#17
Old 11-28-2013, 08:43 AM
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Originally Posted by outlierrn View Post
Umm, what other kind of penises are there?
In the greater LGBTQ community, you will find more than a few folks asserting they have female penises.

I'm staying out of that debate. I just want everyone to get along...
#18
Old 11-28-2013, 09:05 AM
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Quote:
Originally Posted by Lynn Bodoni View Post
Female spotted hyenas have what is called a pseudo-penis. So, a female penis. Basically, it's an oversized clitoris, and the female mates and gives birth through it. She also has a pseudo scrotum.
And whatever crosses you may have to bear, aren't you grateful you never had to give birth through your clitoris?
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Old 11-28-2013, 04:58 PM
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Yeah, and I watched a nature show about hyenas. The next day I went to work and told my co-worker "Both male and female hyenas have penises!"

The co worker said "Maybe that's why they're always laughing."
#20
Old 11-28-2013, 10:45 PM
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Originally Posted by Malacandra View Post
And whatever crosses you may have to bear, aren't you grateful you never had to give birth through your clitoris?
Yes, truly, this is something that I am thankful for. I'm also glad that I don't have to have sex THROUGH my clitoris.

Shall we discuss ovipositors next? They always seemed rather phallic to me.
#21
Old 11-30-2013, 10:57 AM
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If xkcd doesn't have something to say about any given subject, youtube does.
#22
Old 11-30-2013, 12:52 PM
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Quote:
Originally Posted by Qadgop the Mercotan View Post
We have a winner!

DIC with its subsequent clots cutting off blood flow to peripheries like noses, fingers, hands, penises, feet, etc is the primary reason that septic patients need amputations.

Other parts of the body can be clotted off too, which is why some septic patients need hunks of bowel cut out.
I followed a blog for a while that was written by the family and friends of a woman who had a post-partum infection that led to her being a quadruple amputee on dialysis, with short-gut syndrome. In addition to losing all four limbs above the elbows and knees, she also had both kidneys removed, along with almost all of her GI tract. She has gone on TV and said she's happy to be alive, but I just can't imagine that she has ANY quality of life.



I read somewhere that this is what Jim Henson's life would have been like had he survived the massive infection that killed him.

Last edited by nearwildheaven; 11-30-2013 at 12:53 PM.
#23
Old 12-01-2013, 04:56 PM
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Quote:
Originally Posted by nearwildheaven View Post
I followed a blog for a while that was written by the family and friends of a woman who had a post-partum infection that led to her being a quadruple amputee on dialysis, with short-gut syndrome. In addition to losing all four limbs above the elbows and knees, she also had both kidneys removed, along with almost all of her GI tract. She has gone on TV and said she's happy to be alive, but I just can't imagine that she has ANY quality of life.



I read somewhere that this is what Jim Henson's life would have been like had he survived the massive infection that killed him.
Yes I wonder sometimes why the doctors don't withdraw the antibiotics if the person will be a quadruple amputee.
#24
Old 12-01-2013, 05:11 PM
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Some people have adapted to such a life. Granted, there is a LOT to adapt to, but it shouldn't be up to the doctors to determine if life is worth living or not, it should be up to the person who will have to live with the situation.
#25
Old 12-01-2013, 07:15 PM
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Originally Posted by tci707 View Post
Yes I wonder sometimes why the doctors don't withdraw the antibiotics if the person will be a quadruple amputee.
I also remember a bikini model whose life would have been like this had she survived. We all agreed that it was better that she died. IIRC, she was only about 20 years old, and had been in excellent health prior to contracting this infection.
#26
Old 12-01-2013, 07:19 PM
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Originally Posted by nearwildheaven View Post
We all agreed that it was better that she died.
I wonder if she agreed.
#27
Old 12-02-2013, 11:59 AM
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Originally Posted by Qadgop the Mercotan View Post
I wonder if she agreed.
I, for one, would not want to be a quadruple amputee on dialysis, possibly also living on TPNs because of short-gut syndrome. YMMV, of course.
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